Dihydroergotamine (DHE) is a migraine-specific acute medication that can help relieve migraine attacks. DHE is a good migraine treatment option because it comes in many different forms, including nasal sprays, injection and intravenous infusion (delivered directly into the vein).
Dihydroergotamine (DHE), sold under the brand names D.H.E. 45 and Migranal among others, is an ergot alkaloid used to treat migraines. [8][9][10] It is a derivative of ergotamine.
Complete any needed imaging prior to starting DHE. Please use intranasal DHE only if IV DHE is unavailable, or if the patient does not have IV access. Midodrine — OK to continue, but monitor closely for blood pressure changes and worsening orthostatic intolerance.
Dihydroergotamine (DHE) may be considered if first-line treatments like triptans are ineffective. DHE can be administered through IV infusion, injection, or nasal spray. People who are pregnant or ...