The fructosamine blood test measures average blood glucose levels over the two or three weeks prior to when the test is performed. It is sometimes used instead of A1C tests.
Fructosamine is a marker that reflects blood glucose levels over a shorter period compared to HbA1c. It is particularly useful in situations where conditions affecting hemoglobin metabolism may interfere with the accuracy of HbA1c levels.
A serum fructosamine (a glycated protein) level, similar to a hemoglobin A1c level, enables assessment of long-term glycemic control in patients with diabetes mellitus.
Fructosamine (FA), which is a measure of non-enzymatic glycation of circulating proteins including albumin, globulins, and lipoproteins, appears to be a reasonable alternative to HbA1c measurement in situations where HbA1c is not reliable.
Fructosamine is formed when a sugar and a protein (usually albumin, but also globulin, or lipoprotein) are combined [1]. Similarly to HbA1c (glucose + hemoglobin), fructosamine is a measure of the amount of glucose in the blood.
Fructosamine is an alternative glycemic index that has a shorter half-life than HbA1c, and thus, reflects recent (i.e. 1–3 weeks) glycemic status. It primarily originates from the non-enzymatic glycation of albumin (~ 90%), as well as other proteins [53].
Fructosamine measures average blood sugar levels over the past 2-3 weeks. It reflects glycated serum proteins, primarily albumin. This marker can be useful when A1C doesn’t align with self-monitored glucose levels or when conditions like anemia affect A1C accuracy.
Recent blood transfusion can cause an artificially low hemoglobin A1c (HbA1c). Options for follow-up include monitoring home blood sugar readings; checking a fructosamine (glycosylated albumin) level, ...