Prions are biological anomalies – self-replicating, not-alive little particles that can misfold into an unstoppable juggernaut of fatal disease. Prions don't contain genes, and yet they make more of ...
Case Western Reserve University: First atomic-level imaging of lethal prions provides sharpened focus for potential treatments
First atomic-level imaging of lethal prions provides sharpened focus for potential treatments
Science News: ‘The Power of Prions’ explores misfolded proteins’ role in brain diseases
Until now, most prion research explored brain tissue--the end point of infection. But a few investigators are seeking the site where prions pathogenesis begins. And their work is converging on a ...
In functional prions, it is regulated by a physiological signal. Secondly, in pathological prions, once the prions assume an aggregated self-perpetuating form, prion proteins then kill the cell. They ...
The New England Journal of Medicine: Detection of Prions in a Cadaver for Anatomical Practice
Forbes: What Are Viroids? Taking A Peek At The World’s Smallest Pathogens
This is the first article in a series on viroids. Viruses, bacteria, and fungi; most people will have heard of these three major types of disease-causing microbes. Some will also have heard about ...
We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...
MSN: Mechanical model reveals how prions trigger a domino effect to spread misfolded proteins
Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, "mad cow disease" in cattle, yet they can also ...