Trinucleotide Expansion Disorders

Nature: Mechanism of trinucleotide repeat expansion by MutSβ-MutLγ and contraction by FAN1

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In Huntington’s disease, the longer the CAG trinucleotide expansion in a person's huntingtin gene, the sooner his or her motor symptoms start. However, the length of inherited repeats alone does not ...

Repeat expansion disorders, which are responsible for more than 40 neurological diseases, may be more common than clinical data would suggest. Epidemiological studies had estimated that REDs affect ...

MarketWatch: Specific Biologics Inc. to Present Dualase(R) Genome Editing for the Precise Removal of Pathogenic Repeats in Repeat Expansion Disorders at the 28th Annual American Society for ...

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Specific Biologics Inc. to Present Dualase(R) Genome Editing for the Precise Removal of Pathogenic Repeats in Repeat Expansion Disorders at the 28th Annual American Society for ...

EXPANSION definition: the act or process of expanding. See examples of expansion used in a sentence.

The meaning of EXPANSION is expanse. How to use expansion in a sentence.

EXPANSION definition: 1. the increase of something in size, number, or importance: 2. the increase of something in size…. Learn more.

an act of increasing or making something increase in size, amount or importance. Despite the recession the company is confident of further expansion. The expansion of higher education will continue. The book is an expansion of a series of lectures given last year.

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Expansion is the process of becoming greater in size, number, or amount. ...the rapid expansion of private health insurance.

expansion (countable and uncountable, plural expansions) The expansion of metals and plastics in response to heat is well understood. Look up the expansion of 1018 steel at stick welding temps and figure out how far this thing's gonna bend once we weld it up. My new office is in the expansion behind the main building.