Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong health problems. The only cure is a blood and bone marrow transplant, but treatments are available to manage the condition.
La enfermedad de células falciformes (ECF) es el trastorno sanguíneo hereditario más común en los Estados Unidos. En esta hoja informativa, aprenda sobre las causas, los signos y síntomas, el diagnóstico y el tratamiento de la ECF. (Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms ...
Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent. People who have sickle cell trait are sometimes called carriers . Sickle cell trait is different from sickle cell disease.
Sickle cell disease is sometimes called sickle cell anemia. People have sickle cell trait if they inherit a copy of the sickle cell gene from one parent and a copy of the gene for normal hemoglobin, called hemoglobin A, from the other.
The U.S. Food and Drug Administration approved two new gene therapies to treat sickle cell disease — one a gene-editing and the other a gene-addition approach. Nearly 100,000 people in the United States — and millions worldwide — have been diagnosed with this painful, life-threatening genetic blood disease. To help explain the historic importance of this medical milestone, we sat down ...