Growth is the essential ingredient for sustained poverty reduction. The Macroeconomics and Growth Research Program focuses on identifying the contribution of policies and institutional changes to the diversity in growth and aggregate economic performance around the world.
The Macroeconomics, Trade, and Finance Seminar Series is a weekly series hosted by the World Bank's research department that invites leading researchers to present their recent research in a seminar format.
Macroeconomics examines economic performance—output, inflation, interest and exchange rates—guiding monetary and fiscal policies that support equity and sustainable growth.
The series invites leading researchers from the fields of macroeconomics, growth, trade, international integration, and finance to present the results of their most recent research in a seminar format.
Roberto N. Fattal Jaef is a Senior Economist in the Macroeconomics and Growth team of the World Bank’s Development Economics Vice-Presidency. His research interests cover various areas of macroeconomics, with a special emphasis on economic growth. Current and recent research topics include: 1) understanding the role of market distortions for firm level behavior, entrepreneurship, and long ...
From this perch, PINK1’s kinase domain springs into action, phosphorylating ubiquitin, which recruits the ubiquitin ligase Parkin—another PD-linked protein—to tag mitochondria for degradation. While the broad strokes of this process are well-known, precisely how PINK1 remains anchored to the membranes of ailing mitochondria was a puzzle.
These parkin knockout (KO) mice were generated by creating a germline disruption in the parkin gene within exon 3 leading to a truncated transcript coding for the first 95 amino acids of mouse parkin protein fused in-frame with the coding sequence of EGFP (Goldberg et al., 2003). Loss-of-function ...