Lung Squamous cell carcinoma (LSCC) represents the second most common non-small cell lung cancer. Although studies identified adenocarcinoma-like driver mutations in LSCC using next-generation ...
KIT-exon-11 mutations in GISTs correlate with higher partial response rates and improved surgical outcomes with neoadjuvant Gleevec. Non-KIT exon 11 mutations and wild-type KIT/PDGFRA GISTs show less ...
The Conversation: What is a ‘cancer gene’? How genetic mutations lead to cancer
Gaucher disease (GD), the most prevalent lysosomal storage disease characterized by a remarkable degree of clinical variability, results from deleterious mutations in the glucocerebrosidase gene (GBA) ...
Phys.org: Mutations driving evolution are informed by the genome, not random, study suggests
Mutations driving evolution are informed by the genome, not random, study suggests
Fred Hutch: Surprising findings about blood cell mutations bode well for transplant recipients
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